Cyclization of peptides with a number of S-S bonds is a complicated peptide modification Utilized in protein engineering to increase the stability with the peptide. It permits building peptide scaffolds that can be utilized to Display screen peptide or protein ligands in a specific orientation via multiple sulfur-sulfur bonds.
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There are actually A further alternate strategies that could be utilized, for example submit assembly phosphorylation of serine, threonine or tyrosine that contains peptide resins.
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